Can Doxorubicin truly be injected within 6 or 15 minutes without any risk?
After reading several reports, I realised that Mrs Yip(Mdm Ng's) drug was always mentioned to the public (5-fluorouracil) but as for my mum's case, it's just a brief statement saying the drug given can actually be done in 15 minutes.
During the inquiry, senior medical oncologist Dr Soh Lay Tin even "assured" us that "it's ok" to have it injected in 6 minutes.
To me, the infusion clearly exceeded the prescription given by doctor. So how can that be ok?!
How true is the above statement?
6 comments:
famous european oncologist dr. simoncini said that it was found in polls and questionnaires that 75% of doctors themselves would refuse any form of chemotherapy because of its nasty effects on the entire human mechanism etc. if that is so, surely it can't be "okay" to administer it in minutes.
Can Doxorubicin truly be injected within 6 or 15 minutes without any risk?
SURE you can, but that is NOT the issue.
Why do you think the original doctor who wrote the prescription indicated it for 3 days instead of 3 hours. That is his professional judgement.
The is posology (ie the way a medicine can be prescribed as doses) but those are theoretical knowledge based on population study...... But prescribing of medicine is an art, it has to be done (under professional medicical advice) to be titrated according to patient need......
I have no doubt that the doctor (who wrtoe the prescription) has some intended meaning and reason to have it administered over 3 days.... So even if it is SAFE to be done over 6 minute (as IV Bolus) it is WRONG, WORNG and WRONG !!!!!
We are talking about chemo medicine here not panadol.
Just need to ask that Dr Soh Lay Tin whether would she allow the same thing be done to her mother.
Should seriously consider sueing the KKH.
Will pray that your mother will get well soon.
hey im glad u highlighted this blunder and brght it to light to the media regarding the blunder. many of these mistakes are being swept under the carpet by their so caled "compensations".
you are right. despite whether the drug can b administered within 6 mins or not, the fact tt the infusion has clearly exceeded the prescription given by the doctor, it IS a MEDICATION ERROR alr. whether or not it is fatal, it is indeed a medication error which shld nv happen in any case and there is negligence.
do fight for ur mum's case and i hope she'll get well soon! praying for u n ur family.
Hi Mr. Ng,
I was sad to hear the your mom have suffer so much due to KKH mistake. I have check the internet about Doxorubicin, the side effect are as follows:
[edit] Side effects
Acute side-effects of doxorubicin can include nausea, vomiting, and heart arrhythmias. It can also cause neutropenia (a decrease in white blood cells), as well as complete alopecia (hair loss). When the cumulative dose of doxorubicin reaches 550 mg/m², the risks of developing cardiac side effects, including congestive heart failure, dilated cardiomyopathy, and death, dramatically increase. Doxorubicin cardiotoxicity is characterized by a dose-dependent decline in mitochondrial oxidative phosphorylation. Reactive oxygen species, generated by the interaction of doxorubicin with iron, can then damage the myocytes (heart cells), causing myofibrillar loss and cytoplasmic vacuolization. Additionally, some patients may develop palmar plantar erythrodysesthesia, or, "hand-foot syndrome," characterized by skin eruptions on the palms of the hand or soles of the feet, characterized by swelling, pain and erythema [18].
Due to these side effects and its red color, doxorubicin has earned the nickname "red devil"[23] or "red death."[24]
Doxorubucin can also cause reactivation of hepatitis B.[citation needed]
Hope it will help you, and May God Bless your Mother and your Family, Be strong and we will be praying for you.
Hi, during my brother's 6 month battle with cancer, we learned a few things (and not from the bloody doctors who attended to him). Chemo drugs only kill up to 70% of the cancer cells, the body's own immunity system has to take care of the rest. Chemo drugs also kill good healthy cells, hence the various unpleasant side efects. It is imperative that the patient have good nourishment during this trying period. Naturally a positive attitude goes a long way. Avoid discussing the KKH horrors with your mum, just keep her focused on getting well and going home. The hospital is a nasty place, and the longer the stay, the greater the possibility of being infected by MRSA. Take care.
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